The Ulimate GLP-1, Gallstones & Emergency Cholecystectomy FAQ (UK): Symptoms → A&E → Recovery → Diet

Medical disclaimer: This page is lived experience + educational information, not medical advice. If you have severe or worsening pain, fever/chills, jaundice (yellow skin/eyes), persistent vomiting, confusion/fainting, or dark urine + pale stools, seek urgent medical help (UK: 999 / A&E / NHS 111).Affiliate disclosure: Some links may be affiliate links (at no extra cost to you). I’ll always keep this calm and practical: use what helps, ignore what doesn’t, and prioritise professional medical care.

About me (why this page exists)

I’ve lost 7 stone (100lbs+) using GLP-1 weight loss injections (Mounjaro) since January 2025.
I had emergency gallbladder removal surgery (cholecystectomy) in February 2026 (UK/NHS).
This page is the “everything I wish I’d read” guide: symptoms → A&E → surgery → recovery → diet → GLP-1.

Did Mounjaro (or Wegovy/Ozempic) Cause My Gallstones — and Did GLP-1 Play a Role in My Emergency Gallbladder Removal (UK)?

Short answer: GLP-1 meds can be associated with gallbladder events in some people — but in many cases it’s not one single cause. Gallstones are common in the UK, and rapid weight loss itself can increase the risk of gallstones. The important bit is recognising symptoms early and knowing when it’s not “just trapped wind”.

Start here (my best resources)

Emergency checklist (UK)

Go urgent (A&E / 999) if you have:

Severe pain that won’t settle (especially upper right abdomen, centre upper abdomen, or radiating to right shoulder/back)
Fever/chills or you feel seriously unwell
Jaundice (yellow skin/eyes)
Dark urine + pale stools (possible bile duct blockage)
Persistent vomiting / unable to keep fluids down
Confusion, fainting, chest pain that feels cardiac (do not “wait it out”)

Rough decision guide:

Situation	What to do (UK)
Mild discomfort, settles quickly, no fever/jaundice	Monitor, hydrate, avoid fatty meals, book GP if recurrent
Moderate pain lasting > 1–2 hours, recurring episodes	Call NHS 111 for urgent assessment
Severe/worsening pain, fever/chills, jaundice, vomiting, dark urine + pale stools	999 / A&E (possible cholecystitis, bile duct blockage, pancreatitis)

Gallbladder attack vs trapped wind/heartburn (what fooled me)

I spent years thinking I had trapped wind, reflux, or “one of those random back pains”. The pattern that mattered (and I ignored) was repeating episodes that tended to build, radiate, and mess with sleep.

Symptom / clue	More like gallbladder	More like wind/heartburn
Pain location	Upper right / upper centre, radiates to right shoulder/back	Central chest burn, often rising acid sensation
Timing	Often after eating (especially fatty), can last hours	Often improves with antacids/burping, changes with posture
Repetition pattern	Recurrent “attacks”, gradually more frequent over years	More linked to specific foods/stress, not escalating over years
Red flags	Fever, jaundice, dark urine, pale stools, vomiting	Usually none of the above

If you want the deep-dive version: Gallbladder attack vs trapped wind/heartburn (UK).

My timeline (how it built up)

The slow build: For years I had sporadic episodes that started as an ache in the right shoulder/back area, built into pressure, then either moved across the upper abdomen or settled by morning. Over time the attacks became more frequent.

The trigger week: I’d been losing weight on GLP-1, felt generally better, then I had a small run of richer food (for me: a few cheese toasties across the week). Pain started, didn’t behave like my “usual”, escalated hard overnight, and wouldn’t settle.

The moment that mattered: I eventually called for help and ended up in A&E / surgical assessment. Bloodwork showed inflammation/infection markers, an ultrasound followed, and I was admitted. Surgery happened quickly because it wasn’t “routine gallstones” anymore — it was heading into danger territory.

My blunt lesson:

ChatGPT can help you ask better questions. It cannot replace proper medical assessment.
If an “attack” changes pattern (stronger, longer, feverish, yellow, dark urine/pale stools) — treat it as urgent.
Being “tough” is not a flex when your bile duct or pancreas might be involved.

What happens in hospital (UK): tests, terms, and what they’re checking

Test / step	Why they do it	What it can suggest
Vitals + exam	Check stability and pain pattern	Serious infection, dehydration, acute abdomen
Bloods (incl. inflammation markers)	Look for infection/inflammation	Cholecystitis, cholangitis, complications
LFTs / bilirubin	Check bile flow / liver strain	Blocked bile duct (esp. with jaundice/dark urine)
Amylase/lipase	Check pancreas involvement	Pancreatitis risk (urgent)
Ultrasound	Fast imaging for stones/inflammation	Gallstones, thickened gallbladder, duct dilation
MRCP / CT (sometimes)	More detail if ducts/pancreas suspected	Hidden duct stones, complications
ERCP (if duct stone)	Clear bile duct stone	Relieves obstruction and reduces risk

If you want a plain-English NHS decision tool: NHS England – “Making a decision about gallstones” (PDF).

GLP-1 + gallstones: the honest, boring truth (which is what you want)

1) Gallstones are common in the UK. NHS information notes gallstones affect more than 1 in 10 adults in the UK, and many people have no symptoms.

2) Rapid weight loss can raise gallstone risk. Some NHS hospital diet guidance warns that losing weight too quickly (for example > 1kg/week) can increase gallstone formation risk.

3) GLP-1 meds include gallbladder warnings in product information. For example, official product information for Wegovy (semaglutide 2.4 mg) reports cholelithiasis and cholecystitis in clinical trials; and Mounjaro (tirzepatide) product information notes acute gallbladder disease can occur and is associated with weight reduction.

So did Mounjaro “cause” my gallstones?

In my case, it looks more like long-term predisposition + years of build-up, with weight loss (from any method) making the gallbladder “busier” for a while. GLP-1 may be part of the risk picture for some people, but it’s rarely the one and only cause. If you’ve had previous biliary issues, the safe play is monitoring symptoms early and discussing it with your clinician.

Deep dive: Did Mounjaro cause gallstones? (UK)

Recovery after gallbladder removal: what’s normal vs red flags

Keyhole (laparoscopic) cholecystectomy recovery varies — but there are a few repeat patterns.

Symptom	Often normal	Get checked urgently
Shoulder/chest ache	Gas pain from surgery, improves day by day	Breathlessness, crushing chest pain, fainting
Bloating / wind	Common early, improves with walking	Hard swollen abdomen + fever + worsening pain
Constipation	Often from pain meds, dehydration	No stool/gas + vomiting + severe pain
Loose stools/diarrhoea	Can happen after fatty meals early on	Blood, dehydration, persistent fever
Dark urine / pale stools	Sometimes dehydration (dark urine only)	Dark urine + pale stools + jaundice

Helpful reads (based on what people Google post-op):

Diet after gallbladder removal: fat ladder + 7-day meal plan

Without a gallbladder, bile still exists — it’s just not stored and released in one big “squirt” for fatty meals. Early on, the practical trick is smaller portions, lower fat, and a gentle ramp back up.

Fat ladder (reintroduction table)

Stage	Goal	Foods that usually behave	Foods to delay
Stage 1 Days 1–3	Settle stomach, avoid “fat shock”	Toast, crackers, oats, rice, bananas, applesauce, soup, low-fat yoghurt	Fried food, cheese overload, creamy sauces, alcohol
Stage 2 Days 4–7	Gentle protein + fibre	Chicken/turkey, white fish, potatoes, carrots, peas, lentils (small portions), low-fat dairy	Spicy, greasy, large salads (too much raw fibre too soon)
Stage 3 Week 2–3	Reintroduce moderate fat	Eggs, olive oil (small), nut butter (small), salmon (small portion)	Takeaways, pastries, big cheese meals
Stage 4 Week 4+	Normalise, learn your triggers	Balanced meals, normal fibre, occasional treats (test slowly)	Your personal “never again” list (everyone has one)

7-day gentle meal plan (UK-friendly)

Notes: Keep portions modest, eat slower than you think you need to, and aim for a short walk after meals if you can. If you’re on GLP-1, nausea can overlap with post-op digestion — keep it simple.

Day	Breakfast	Lunch	Dinner	Snack ideas
1	Oats + banana	Chicken noodle soup	Rice + white fish + carrots	Low-fat yoghurt, crackers
2	Toast + honey / jam	Baked potato + tuna (light mayo)	Turkey mince + rice (low-oil)	Apple, rice cakes
3	Overnight oats	Egg sandwich (thin spread)	Chicken + mash + peas	Low-fat yoghurt
4	Greek yoghurt (low-fat) + berries	Soup + bread	White fish tacos (no heavy sauces)	Banana, crackers
5	Scrambled eggs	Chicken salad (small portion, easy veg)	Pasta + tomato sauce + lean protein	Fruit, yoghurt
6	Oats + peanut butter (tiny amount)	Wrap + turkey + light dressing	Salmon (small) + rice + veg	Rice cakes
7	Toast + eggs	Baked potato + beans	Curry-style spices (mild) + chicken + rice	Yoghurt, fruit

Upgrade-order table (if digestion is messy)

Try this first	Why
Smaller meals, lower fat for a bit	Prevents “bile overload” feeling after big fatty meals
Walk after meals + hydration	Helps gas, constipation, appetite regulation (especially on GLP-1)
Add fibre slowly (oats, bananas, then veg)	Too much fibre too soon can backfire
If diarrhoea persists: ask GP about bile acid malabsorption (BAD/BAM)	Some people need targeted treatment rather than “diet hacks”

Optional support (calm affiliate bridge)

I used Lily & Loaf supplements as part of my wider “get healthier and reduce inflammation” push. This is not a replacement for medical care (and it won’t fix a blocked duct). If you want to browse them, do it with your clinician/pharmacist in mind and avoid miracle thinking:

Lily & Loaf (affiliate link) (discount code: ALAN10, if active)

Watch (video picks)

Video pick #1: My emergency surgery diary — useful if you want the real timeline, what A&E felt like, and the post-op reality.

Video pick #2: The mega FAQ video — best if you want symptoms, red flags, diet, recovery, and GLP-1 questions answered in one sitting.

FAQs (People Also Ask)

Did Mounjaro cause my gallstones?

Not always. Gallstones are common and can exist silently for years. GLP-1 meds can be associated with gallbladder events in some people, and rapid weight loss can increase risk too. The safest approach is knowing red flags and getting assessed early.

How do I know it’s gallbladder and not trapped wind?

Gallbladder attacks often build, last longer, radiate to the right shoulder/back, and can follow meals. Red flags (fever, jaundice, dark urine + pale stools, persistent vomiting) push it into urgent territory.

What does dark urine + pale stools mean?

It can indicate bile isn’t reaching the gut (possible duct blockage), especially if paired with jaundice or itching. Treat that as urgent.

How long does a gallbladder attack last?

It can be 30 minutes to several hours. If it doesn’t settle, keeps returning, or comes with red flags, don’t wait it out.

Can gallstones cause pancreatitis?

Yes — if a stone blocks the duct that affects the pancreas. Severe upper abdominal pain with vomiting/fever needs urgent assessment.

What tests diagnose gallstones in the UK?

Often blood tests (inflammation markers, LFTs/bilirubin) plus ultrasound. Sometimes CT/MRCP, and ERCP if duct stones are suspected.

What is cholecystitis?

Inflammation/infection of the gallbladder, often due to a blocked duct. It typically needs urgent medical care.

Is gallbladder removal always emergency?

No. Many cases are elective. But if infection/complications are suspected, it can become urgent quickly.

How long is recovery after laparoscopic cholecystectomy?

Many people improve week by week, but digestion can take longer to settle. Follow your surgical team’s advice and reintroduce fats gradually.

Is diarrhoea after gallbladder removal normal?

It can happen, especially after fatty foods. If persistent, ask about bile acid malabsorption (BAD/BAM).

Can I go back on Mounjaro/Wegovy after gallbladder removal?

Some people do, but timing and dose should be discussed with your prescribing clinician, especially after surgery and while appetite/digestion are still settling.

Official sources & stats (UK)

Internal related reading (UK)

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