My 6-Stone Mounjaro Journey (2025–2026): Real Results, Side Effects & What Actually Worked

This page exists for one reason: context.

GLP-1 medications like Mounjaro generate a huge amount of search traffic — but very little of it is grounded in long‑term, real‑world experience.

In 2025–2026, I lost over 6 stone (86lbs) using Mounjaro (tirzepatide), prescribed through a regulated UK provider. I documented the process openly, including the uncomfortable parts most people gloss over.

This hub brings everything together: what changed, what broke, what helped, and how I made it sustainable.

Who this journey is for

This hub is for you if:

• You’re considering starting Mounjaro or another GLP‑1
• You’ve started but are struggling with side effects
• You’re losing weight but feel tired, nauseous, or inconsistent
• You want evidence‑led information plus lived experience

It’s not a transformation flex. It’s a reference point.

Quick links (core resources)

• GLP‑1 medication access (UK): https://www.alanspicer.com/mounjaro
• GLP‑1 weight loss category: https://alanspicer.com/category/glp1-weight-loss/
• Daily nutrition & gut support: https://www.alanspicer.com/lilyandloaf

The starting point

At the beginning of 2025:

• I was severely overweight
• My energy was inconsistent
• Food noise dominated decision‑making
• Previous weight‑loss attempts hadn’t stuck

Mounjaro wasn’t a magic switch — but it changed the conditions under which change became possible.

The headline result

• Weight lost: 6+ stone (86lbs)
• Timeframe: ~12 months
• Medication: Mounjaro (tirzepatide)
• Access route: UK-regulated provider
• Approach: Medication + systems (nutrition, hydration, behaviour)

What matters here is not the number itself, but the rate and sustainability. Rapid early loss slowed naturally over time as my body adapted — which is exactly what most clinicians expect with GLP‑1 use.

What Mounjaro changed (and what it didn’t)

What changed

• Appetite dropped dramatically
• Portion sizes became naturally smaller
• Food noise reduced
• Late‑night eating stopped

What didn’t

• Nutrition still mattered
• Hydration became more important
• Side effects still happened
• Routines still broke without structure

The side effects — honestly

Over the course of the year, I experienced most of the commonly reported GLP‑1 side effects at different stages:

• Nausea (early weeks and dose increases)
• Constipation (intermittent but persistent without systems)
• Fatigue (usually hydration- or protein-related)
• Headaches (often dehydration-linked)
• Appetite suppression strong enough to under‑eat

None of these were constant — but all of them appeared predictably when routines slipped.

Dedicated deep dives (evidence‑led)

• Mounjaro nausea (causes + fixes): https://alanspicer.com/mounjaro-nausea/
• Mounjaro constipation (why it happens): https://alanspicer.com/mounjaro-constipation/
• Hydration & electrolytes on GLP‑1: https://alanspicer.com/hydration-electrolytes-glp1/

The systems that made it sustainable

This is where most GLP‑1 journeys succeed or fail.

Medication reduced appetite — systems reduced friction.

Without systems, side effects compound. With systems, they fade.

Weight loss didn’t come from motivation. It came from removing friction.

The systems that mattered most:

1️⃣ Protein‑first eating

Low appetite makes protein easy to miss.

What worked: – Eating protein first – Stopping when full – Keeping meals simple

Full guide: – What to eat on Mounjaro: https://alanspicer.com/what-to-eat-on-mounjaro/

2️⃣ Hydration as a daily system

Many side effects were actually dehydration in disguise.

Once hydration became intentional: – Nausea reduced – Constipation improved – Energy stabilised

Guide: – https://alanspicer.com/hydration-electrolytes-glp1/

3️⃣ Digestive and nutritional support

Eating less makes gaps more likely.

Rather than chasing fixes, I focused on daily consistency:

• Fibre
• Gut comfort
• Micronutrient coverage

What I use: – https://www.alanspicer.com/lilyandloaf

Deep dive: – https://alanspicer.com/daily-essentials-the-best-supplements-for-sustained-weight-loss-on-glp-1s-by-lilyloaf-2026-guide/

The video diary (full transparency)

I documented the journey publicly — including bad weeks, plateaus, and side effects — as they happened.

📺 YouTube diary:
https://www.youtube.com/@AlanSpicerisLosingIt

This exists so people can see what this actually looks like over time.

What I’d do differently if starting again

• Take hydration seriously from day one
• Eat smaller meals sooner
• Avoid large, fatty meals early on
• Treat nutrition as a system, not a reaction

Most side effects weren’t failures — they were feedback.

Frequently asked questions

Is losing 6 stone on Mounjaro safe?
Safety depends on medical oversight, rate of loss, and nutritional support. Rapid loss without systems increases side‑effect risk.

How quickly did the weight come off?
Loss was faster early on and slowed over time — a pattern commonly reported with GLP‑1 medications.

Did appetite disappear completely?
No. Hunger reduced, but cues changed. Learning when and what to eat mattered.

Did you have weeks where nothing moved?
Yes. Plateaus happened and resolved without extreme intervention.

What mattered more than willpower?
Hydration, protein intake, and routine consistency.

Is losing 6 stone on Mounjaro typical?
Results vary. Medication creates conditions for weight loss, but outcomes depend on consistency, dose, and systems.

Did you regain weight?
No — the focus was sustainability, not speed.

Was it hard?
Not in the way traditional dieting is, but it required adjustment.

Would you recommend Mounjaro?
With proper medical oversight and realistic expectations, it can be a powerful tool.

How to get started (UK)

If you’re considering GLP‑1 treatment in the UK:

• Medication access & eligibility: https://www.alanspicer.com/mounjaro

If you’re already on treatment and struggling with tolerance, energy, or consistency:

• Daily nutrition & gut support: https://www.alanspicer.com/lilyandloaf

Browse all related, indexed GLP‑1 guides: – https://alanspicer.com/category/glp1-weight-loss/

This hub links only to live, published posts that sit within the GLP‑1 weight‑loss category, helping search engines clearly understand topical relationships.

Transparency: Some links are affiliate links. They support ongoing free GLP‑1 education at no extra cost to you.