Related reading: If you’re looking at immune health beyond seasonal illness, see: – Nipah virus & GLP‑1 immune health: https://alanspicer.com/nipah-virus-glp-1-immune-health
Flu season arrives every year, but if you’re taking a GLP‑1 medication such as Mounjaro, Wegovy or Ozempic, it often raises a familiar concern:
Does eating less affect my immune system — and should I approach flu season differently while on GLP‑1?
This guide is written to answer that clearly, calmly, and responsibly. It focuses on nutrition, recovery, and practical support — not fear, hype, or unrealistic supplement claims.
What Is Seasonal Flu?
Seasonal influenza (flu) is a common viral respiratory illness that circulates every year, typically peaking in autumn and winter.
Key points: – Caused by influenza A and B viruses – Spreads through close contact, coughs and sneezes – Symptoms range from mild to severe – Most people recover fully, but recovery can be harder during physical stress or nutritional deficiency
Flu is not new or emerging — but it does increase demand on the immune system, especially during illness and recovery.
Are People on GLP‑1 Medications at Higher Risk During Flu Season?
There is no evidence that GLP‑1 medications weaken the immune system or directly increase flu risk.
GLP‑1 receptor agonists: – Regulate appetite – Slow digestion – Improve blood‑sugar control
They do not suppress immune function.
However, because people on GLP‑1 medications usually eat less overall, nutritional adequacy matters more — particularly during flu season when recovery demands are higher.
My 6-Stone Mounjaro Journey (2025–2026): Real Results, Side Effects & What Actually Worked
Immune Health on GLP‑1: What Matters Most in Flu Season
Immune resilience is not about avoiding illness completely. It’s about supporting normal immune function so your body can respond and recover efficiently.
Protein Intake
Protein is essential for immune cell production, antibody formation and tissue repair. During flu season, consistently low protein intake can slow recovery — especially when appetite is reduced.
Key Micronutrients
Several micronutrients are closely linked to normal immune function:
– Zinc – supports immune cell development
– Selenium – contributes to antioxidant defence
– Magnesium – supports energy metabolism, sleep and stress regulation
These nutrients are easy to under‑consume when appetite is suppressed.
Omega‑3 Fatty Acids
Omega‑3s help regulate inflammatory responses, which matters during illness and recovery. Reduced food volume often means reduced oily fish intake.
Gut Health
A significant portion of immune signalling occurs via the gut. GLP‑1 medications can alter digestion, making gentle fibre and hydration support more relevant during flu season.
Hydration
Fever, loss of appetite, and reduced thirst can all increase the risk of dehydration. Hydration consistency is one of the most overlooked aspects of immune resilience.
Supporting Immune Health on GLP‑1 During Flu Season (Practical Solutions)
When people search for solutions during flu season, they’re not looking for guarantees — they’re looking for what actually helps when appetite is reduced and recovery matters.
Protein Intake (Foundation of Immune Recovery)
Adequate protein intake is one of the most important — and most commonly missed — factors during flu season on GLP‑1.
Protein is required for immune cell production, antibody formation and tissue repair. When appetite is suppressed by GLP‑1 medications and further reduced by flu symptoms, intake can drop quickly.
Practical guidance: prioritise protein earlier in the day, choose protein‑dense foods in smaller portions, and aim for consistency rather than large meals.

Zinc & Selenium (Micronutrients for Immune Function)
Zinc and selenium both contribute to the normal function of the immune system and are frequently under‑consumed during calorie restriction.
Common reasons intake drops on GLP‑1 include reduced red meat, seafood and dietary variety.
Real product links:
– Zinc: https://lilyandloaf.com/products/zinc?aff=12026950
– Selenium: https://lilyandloaf.com/products/selenium?aff=12026950
Omega‑3 Fatty Acids (Inflammation Balance During Illness)
Omega‑3 fatty acids help regulate inflammatory responses rather than overstimulating immunity — an important distinction during flu recovery.
Lower food volume and reduced oily fish intake make supplementation more relevant for some people.
Real product link: – Omega‑3: https://lilyandloaf.com/products/omega-3-6-9-1000mg-organic?aff=12026950
Magnesium (Sleep, Stress & Immune Resilience)
Sleep quality and stress regulation are closely linked to immune resilience. Magnesium supports normal muscle and nerve function, sleep quality and stress response.
During flu season, reduced intake combined with illness‑related stress can make magnesium adequacy more relevant.
– Magnesium: https://lilyandloaf.com/products/magnesium?aff=12026950
Gut Support & Fibre (Immune Signalling Support)
A large proportion of immune activity is associated with the gut. GLP‑1 medications can slow digestion and alter bowel habits, making gentle fibre support more appropriate than aggressive approaches.
– Prebiotic Fibre: https://lilyandloaf.com/products/pre-pro-15?aff=12026950
When You’re Ill and Not Hungry (Protein & Hydration Basics)
One of the biggest challenges during flu season on GLP‑1 medications is low appetite combined with illness.
If you’re unwell and struggling to eat normally, focus on two priorities only:
- Protein, in small amounts
Smaller, protein‑focused options are often better tolerated: – Yogurt or skyr – Protein shakes or smoothies – Soups with added protein – Soft foods eaten slowly - Hydration, consistently
Aim for frequent small sips rather than large drinks. Water, diluted electrolytes and clear broths are often easiest to tolerate.
Getting something in consistently matters far more than eating perfectly for a few days.
Quick Comparison: Food vs Supplements on GLP‑1 (Flu Season)
| Supplement | Why intake may drop | How supplements help | Lily & Loaf |
| Zinc & Selenium | Smaller meals, less meat & seafood | Maintains normal immune function | https://lilyandloaf.com/products/zinc?aff=12026950 |
| Omega‑3 | Reduced oily fish intake | Supports inflammation balance | https://lilyandloaf.com/products/omega-3-6-9-1000mg-organic?aff=12026950 |
| Magnesium | Lower calories & hydration shifts | Supports sleep & recovery | https://lilyandloaf.com/products/magnesium?aff=12026950 |
| Fibre / Gut Support | Reduced food variety | Supports gut‑immune signalling | https://lilyandloaf.com/products/pre-pro-15?aff=12026950 |
Frequently Asked Questions (FAQ)
Does flu hit harder if you’re eating less on GLP‑1?
It can. Reduced intake may increase the risk of protein or micronutrient gaps, which can slow recovery.
Do GLP‑1 medications weaken the immune system?
No. There is no evidence that GLP‑1 receptor agonists suppress immune function.
Can supplements prevent flu?
No. Supplements do not prevent or treat viral infections. They support nutritional adequacy only.
Is it safe to take supplements with Mounjaro or Wegovy?
For most people, common supplements are well tolerated. Always check with a healthcare professional if unsure.
What matters most for recovery during flu season on GLP‑1?
Adequate protein, hydration, sleep and avoiding prolonged nutrient gaps.

Start Here: Daily Essentials Bundle
If you prefer a simple approach, many people start with a Daily Essentials bundle that covers common gaps while eating less.
Real product link: https://lilyandloaf.com/products/daily-essentials-bundle?aff=12026950
This is about nutritional coverage, not flu prevention.
The Bottom Line
Flu season doesn’t require panic — especially if you’re on GLP‑1.
Focus on: – Consistent nutrition – Hydration – Sleep and recovery
Supporting immune health while eating less is about steady habits, not fear‑driven supplements.








